FMR1 Gray Zone Alleles: Association with Parkinson Disease in Women?

PURPOSE: Carriers of fragile X mental retardation 1 (FMR1) repeat expansions in the premutation range (55–200 CGG repeats), especially males, often develop tremor, ataxia, and parkinsonism.(1–2) These neurological signs are believed to be due to elevated levels of expanded CGG repeat FMR1 mRNA. The...

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Detalhes bibliográficos
Main Authors: Hall, Deborah A, Berry-Kravis, Elizabeth, Zhang, Wenting, Tassone, Flora, Spector, Elaine, Zerbe, Gary, Hagerman, Paul J, Ouyang, Bichun, Leehey, Maureen A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934001/
https://ncbi.nlm.nih.gov/pubmed/21567456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23755
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