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THE INTERLEUKIN-1 FAMILY: BACK TO THE FUTURE

Interleukin-1 (IL-1) is a central mediator of innate immunity and inflammation. The IL-1 family includes 7 ligands with agonist activity (IL-1α and β, IL-18, IL-33, IL-36α, β, γ), three receptor antagonists (IL-1Ra, IL-36Ra, IL-38) and an anti-inflammatory cytokine (IL-37). Members of the IL-1 Recep...

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Bibliographic Details
Main Authors: Garlanda, Cecilia, Dinarello, Charles A., Mantovani, Alberto
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933951/
https://ncbi.nlm.nih.gov/pubmed/24332029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.11.010
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