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Paroxetine Attenuates the Development and Existing Pain in a Rat Model of Neurophatic Pain
Background: P2X4 receptor (P2X4R), a purinoceptor expressed in activated spinal microglia, plays a key role in the pathogenesis of neuropathic pain. Spinal nerve injury induces up-regulation of P2X4R on activated microglia in the spinal cord, and blockade of this receptor can reduce neuropathic pain...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Pasteur Institute of Iran
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933918/ https://ncbi.nlm.nih.gov/pubmed/24518550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.1282.2013 |
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