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Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway
INTRODUCTION: There is currently no curative treatment for melanoma once the disease spreads beyond the original site. Although activation of the PI3K/Akt pathway resulting from genetic mutations and epigenetic deregulation of its major regulators is known to cause resistance of melanoma to therapeu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933667/ https://ncbi.nlm.nih.gov/pubmed/24600206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S53568 |
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