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Death ligand concentration and the membrane proximal signaling module regulate the type 1/type 2 choice in apoptotic death signaling
Apoptotic death pathways are frequently activated by death ligand induction and subsequent activation of the membrane proximal signaling module. Death receptors cluster upon binding to death ligands, leading to formation of a membrane proximal death-inducing-signaling-complex (DISC). In this membran...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933635/ https://ncbi.nlm.nih.gov/pubmed/24592294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11693-013-9124-4 |
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