Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif.

Elements responsible for dexamethasone responsiveness of CYP3A23, a major glucocorticoid-inducible member of the CYP3A gene family, have been identified. DNase I footprint analysis of the proximal promoter region revealed three protected sites (sites A, B, and C) within the sequence defined by -167...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Huss, J M, Wang, S I, Astrom, A, McQuiddy, P, Kasper, C B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4666
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