Genetic Polymorphisms of Metabolic Enzymes and the Pharmacokinetics of Indapamide in Taiwanese Subjects

To understand the genetic makeup and impact on pharmacokinetics (PK) in the Taiwanese population, we analyzed the pharmacogenetic (PG) profile and demonstrated its effects on enzyme metabolism using indapamide as an example. A multiplex mass spectrometry method was used to examine the single nucleot...

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Bibliographic Details
Main Authors: Wang, Teng-Hsu, Hsiong, Cheng-Huei, Ho, Hsin-Tien, Shih, Tung-Yuan, Yen, San-Jan, Wang, Hui-Hung, Wu, Jer-Yuarn, Kuo, Benjamin Pei-Chung, Chen, Yuan-Tsong, Ho, Shung-Tai, Hu, Oliver Yoa-Pu
Format: Artigo
Language:Inglês
Published: Springer US 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933584/
https://ncbi.nlm.nih.gov/pubmed/24357089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9535-x
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