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Anti-HLA antibodies of predetermined specificity: a chemically synthesized peptide induces antibodies specific for HLA-A,B heavy chain.

A chemically synthesized dodecapeptide (Asp-Ala-Ala-Ser-Pro-Arg-Glu-Glu-Pro-Arg-Ala-Pro), consisting of residues 39 through 50 of the HLA-B7 heavy chain sequence and containing a highly hydrophilic hexapeptide segment (Pro-Arg-Glu-Glu-Pro-Arg), induced antibodies that bound specifically to free HLA-...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Church, W R, Walker, L E, Houghten, R A, Reisfeld, R A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393351/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6571999/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.1.255
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