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Efficacy and safety of febuxostat in the treatment of hyperuricemia in stable kidney transplant recipients

BACKGROUND: Post-transplant hyperuricemia (PTHU), defined as serum uric acid concentration ≥7.0 mg/dL or need for treatment with allopurinol or benzbromarone, reduces long-term allograft survival in kidney transplant recipients. Febuxostat, a new nonpurine selective xanthine oxidase inhibitor, is we...

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Bibliographic Details
Main Authors: Sofue, Tadashi, Inui, Masashi, Hara, Taiga, Nishijima, Yoko, Moriwaki, Kumiko, Hayashida, Yushi, Ueda, Nobufumi, Nishiyama, Akira, Kakehi, Yoshiyuki, Kohno, Masakazu
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933431/
https://ncbi.nlm.nih.gov/pubmed/24600205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S56597
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