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Learning the molecular mechanisms of the reprogramming factors: let’s start from microRNAs

Induced reprogramming of somatic cells has had a great impact on stem cell research, and the reprogramming technologies have evolved from four transgenic factors (Oct4, Sox2, Klf4, and c-Myc; OSKM) to just a few microRNAs (mainly miR-290/302 seed family). Despite these advances, the molecular events...

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Detalles Bibliográficos
Autores principales: Yang, Chao-Shun, Rana, Tariq M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933261/
https://ncbi.nlm.nih.gov/pubmed/23037570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mb25088h
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