Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells

BACKGROUND: Genistein (Gen) exhibits anti-mutagenic and anti-metastatic activities in hepatoma cell lines. Gen has suppressive effects on tumor growth and angiogenesis in nude mice. Gen suppresses the enzymatic activity of matrix metalloproteinase (MMP)-9; however, the mechanism underlying its anti-...

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Main Authors: Wang, Shulhn-Der, Chen, Bor-Chyuan, Kao, Shung-Te, Liu, Ching-Ju, Yeh, Chia-Chou
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933236/
https://ncbi.nlm.nih.gov/pubmed/24433534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-26
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