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The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory

The somatic mutation theory (SMT) of cancer has been and remains the prevalent theory attempting to explain how neoplasms arise and progress. This theory proposes that cancer is a clonal, cell-based disease, and implicitly assumes that quiescence is the default state of cells in multicellular organi...

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Detalhes bibliográficos
Main Authors: Soto, Ana M., Sonnenschein, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933226/
https://ncbi.nlm.nih.gov/pubmed/21503935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201100025
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