Protein carbonylation, cellular dysfunction, and disease progression

Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a widespread indicator of severe oxidative damage and disease-derived protein dysfunction. Whereas moderately carbonylated proteins are degraded by the proteasomal system,...

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Bibliographic Details
Main Authors: Dalle-Donne, Isabella, Aldini, Giancarlo, Carini, Marina, Colombo, Roberto, Rossi, Ranieri, Milzani, Aldo
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2006
Subjects:
Phenomenin Review Series
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933129/
https://ncbi.nlm.nih.gov/pubmed/16796807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2006.tb00407.x
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