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α - synuclein and Parkinson’s disease: the first roadblock
α-synuclein gene mutations are major underlying genetic defects known in familial juvenile onset Parkinson’s disease (PD), and α-synuclein is a major constituent of Lewy Bodies, the pathological hallmark of PD. The normal cellular function of α-synuclein has been elusive, and its exact etiological m...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley & Sons, Ltd
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933078/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2755/jcmm010.004.04 |
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