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A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation

Here we report on a case of Philadelphia chromosome positive B lymphoblastic leukemia (Ph(+)ALL), which developed following a long duration of essential thrombocythemia (ET). A mutational analysis of Janus Kinase 2 (JAK2) revealed that the V617F mutation was present in granulocytes and in hematopoie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nagai, Yuya, Kawahara, Masahiro, Sugino, Noriko, Shimazu, Yayoi, Hishizawa, Masakatsu, Yamashita, Kouhei, Kadowaki, Norimitsu, Takaori-Kondo, Akifumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932988/
https://ncbi.nlm.nih.gov/pubmed/24528501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-6
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