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Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11

Inhibitory killer cell Ig-like receptors (KIRs) are known to recognize HLA ligands mainly of the HLA-C and Bw4 groups, but the ligands for KIRs are poorly understood. We report here the identification of the cognate ligand for the activating KIR 2DS2 as HLA-A*11:01. The crystal structure of the KIR2...

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Detalhes bibliográficos
Main Authors: Liu, Jingxian, Xiao, Ziwei, Ko, Hui Ling, Shen, Meixin, Ren, Ee Chee
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932910/
https://ncbi.nlm.nih.gov/pubmed/24550293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322052111
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