Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells

Worldwide dissemination of antibiotic resistance in bacteria is facilitated by plasmids that encode postsegregational killing (PSK) systems. These produce a stable toxin (T) and a labile antitoxin (A) conditioning cell survival to plasmid maintenance, because only this ensures neutralization of toxi...

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Detalhes bibliográficos
Main Authors: Pimentel, Belén, Nair, Radhika, Bermejo-Rodríguez, Camino, Preston, Mark A., Agu, Chukwuma A., Wang, Xindan, Bernal, Juan A., Sherratt, David J., de la Cueva-Méndez, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932891/
https://ncbi.nlm.nih.gov/pubmed/24449860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308241111
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