Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

Recent historical periods in Europe have been characterized by severe epidemic events such as plague, smallpox, or influenza that shaped the immune system of modern populations. This study aims to identify signals of convergent evolution of the immune system, based on the peculiar demographic histor...

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Hlavní autoři: Laayouni, Hafid, Oosting, Marije, Luisi, Pierre, Ioana, Mihai, Alonso, Santos, Ricaño-Ponce, Isis, Trynka, Gosia, Zhernakova, Alexandra, Plantinga, Theo S., Cheng, Shih-Chin, van der Meer, Jos W. M., Popp, Radu, Sood, Ajit, Thelma, B. K., Wijmenga, Cisca, Joosten, Leo A. B., Bertranpetit, Jaume, Netea, Mihai G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932890/
https://ncbi.nlm.nih.gov/pubmed/24550294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317723111
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