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Phosphorylation releases constraints to domain motion in ERK2
Protein motions control enzyme catalysis through mechanisms that are incompletely understood. Here NMR (13)C relaxation dispersion experiments were used to monitor changes in side-chain motions that occur in response to activation by phosphorylation of the MAP kinase ERK2. NMR data for the methyl si...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932853/ https://ncbi.nlm.nih.gov/pubmed/24550275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318899111 |
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