Tumour T(1) changes in vivo are highly predictive of response to chemotherapy and reflect the number of viable tumour cells – a preclinical MR study in mice

BACKGROUND: Effective chemotherapy rapidly reduces the spin–lattice relaxation of water protons (T(1)) in solid tumours and this change (ΔT(1)) often precedes and strongly correlates with the eventual change in tumour volume (TVol). To understand the biological nature of ΔT(1), we have performed stu...

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Detalhes bibliográficos
Main Authors: Weidensteiner, Claudia, Allegrini, Peter R, Sticker-Jantscheff, Melanie, Romanet, Vincent, Ferretti, Stephane, McSheehy, Paul MJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932835/
https://ncbi.nlm.nih.gov/pubmed/24528602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-88
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