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The Sensitive Balance Between the Fully Folded and Locally Unfolded Conformations of a Model Peroxiredoxin()
To reduce peroxides, peroxiredoxins (Prx) require a key ‘peroxidatic’ cysteine, that in a substrate-ready fully folded (FF) conformation becomes oxidized to sulfenic acid, and then after a local unfolding (LU) of the active site, forms a disulfide bond with a second ‘resolving’ Cys. For Salmonella t...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932808/ https://ncbi.nlm.nih.gov/pubmed/24175952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4011573 |
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