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Targeting the Autophagy Pathway Using Ectopic Expression of Beclin 1 in Combination with Rapamycin in Drug-Resistant v-Ha-ras-Transformed NIH 3T3 Cells
The effectiveness of an apoptosis-targeting therapy may be limited in tumor cells with defects in apoptosis. Recently, considerable attention in the field of cancer therapy has been focused on the mammalian rapamycin target (mTOR), inhibition of which results in autophagic cell death. In our study u...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korea Society for Molecular and Cellular Biology
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932692/ https://ncbi.nlm.nih.gov/pubmed/21350938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0034-6 |
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