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Biochemical and Morphological Effects of Hypoxic Environment on Human Embryonic Stem Cells in Long-Term Culture and Differentiating Embryoid Bodies

The mammalian reproductive tract is known to contain 1.5-5.3% oxygen (O(2)), but human embryonic stem cells (hESCs) derived from preimplantation embryos are typically cultured under 21% O(2) tension. The aim of this study was to investigate the effects of O(2) tension on the long-term cul-ture of hE...

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Detalhes bibliográficos
Main Authors: Lim, Hee-Joung, Han, Jiyou, Woo, Dong-Hun, Kim, Sung-Eun, Kim, Suel-Kee, Kang, Hee-Gyoo, Kim, Jong-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Korea Society for Molecular and Cellular Biology 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932683/
https://ncbi.nlm.nih.gov/pubmed/21347709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0016-8
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