A role for XRCC2 gene polymorphisms in breast cancer risk and survival

BACKGROUND: The XRCC2 gene is a key mediator in the homologous recombination repair of DNA double strand breaks. We hypothesised that inherited variants in the XRCC2 gene might also affect susceptibility to, and survival from, breast cancer. METHODS: We genotyped 12 XRCC2 tagging SNPs in 1,131 breas...

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Библиографические подробности
Главные авторы: Lin, Wei-Yu, Camp, Nicola J., Cannon-Albright, Lisa A., Allen-Brady, Kristina, Balasubramanian, Sabapathy, Reed, Malcolm W., Hopper, John L., Apicella, Carmel, Giles, Graham G, Southey, Melissa C., Milne, Roger L., Perez, Jose I.A., Rodríguez, Primitiva M., Benítez, Javier, Grundmann, Magdalena, Dubrowinskaja, Natalia, Park-Simon, Tjoung-Won, Dörk, Thilo, Garcia-Closas, Montserrat, Figueroa, Jonine, Sherman, Mark, Lissowska, Jolanta, Easton, Douglas F, Dunning, Alison M, Rajaraman, Preetha, Sigurdson, Alice J., Doody, Michele M., Linet, Martha S., Pharoah, Paul D., Schmidt, Marjanka K., Cox, Angela
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932658/
https://ncbi.nlm.nih.gov/pubmed/21632523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2011-100018
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