A role for XRCC2 gene polymorphisms in breast cancer risk and survival

BACKGROUND: The XRCC2 gene is a key mediator in the homologous recombination repair of DNA double strand breaks. We hypothesised that inherited variants in the XRCC2 gene might also affect susceptibility to, and survival from, breast cancer. METHODS: We genotyped 12 XRCC2 tagging SNPs in 1,131 breas...

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主要な著者: Lin, Wei-Yu, Camp, Nicola J., Cannon-Albright, Lisa A., Allen-Brady, Kristina, Balasubramanian, Sabapathy, Reed, Malcolm W., Hopper, John L., Apicella, Carmel, Giles, Graham G, Southey, Melissa C., Milne, Roger L., Perez, Jose I.A., Rodríguez, Primitiva M., Benítez, Javier, Grundmann, Magdalena, Dubrowinskaja, Natalia, Park-Simon, Tjoung-Won, Dörk, Thilo, Garcia-Closas, Montserrat, Figueroa, Jonine, Sherman, Mark, Lissowska, Jolanta, Easton, Douglas F, Dunning, Alison M, Rajaraman, Preetha, Sigurdson, Alice J., Doody, Michele M., Linet, Martha S., Pharoah, Paul D., Schmidt, Marjanka K., Cox, Angela
フォーマット: Artigo
言語:Inglês
出版事項: 2011
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932658/
https://ncbi.nlm.nih.gov/pubmed/21632523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2011-100018
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