A role for XRCC2 gene polymorphisms in breast cancer risk and survival

BACKGROUND: The XRCC2 gene is a key mediator in the homologous recombination repair of DNA double strand breaks. We hypothesised that inherited variants in the XRCC2 gene might also affect susceptibility to, and survival from, breast cancer. METHODS: We genotyped 12 XRCC2 tagging SNPs in 1,131 breas...

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Detalhes bibliográficos
Main Authors: Lin, Wei-Yu, Camp, Nicola J., Cannon-Albright, Lisa A., Allen-Brady, Kristina, Balasubramanian, Sabapathy, Reed, Malcolm W., Hopper, John L., Apicella, Carmel, Giles, Graham G, Southey, Melissa C., Milne, Roger L., Perez, Jose I.A., Rodríguez, Primitiva M., Benítez, Javier, Grundmann, Magdalena, Dubrowinskaja, Natalia, Park-Simon, Tjoung-Won, Dörk, Thilo, Garcia-Closas, Montserrat, Figueroa, Jonine, Sherman, Mark, Lissowska, Jolanta, Easton, Douglas F, Dunning, Alison M, Rajaraman, Preetha, Sigurdson, Alice J., Doody, Michele M., Linet, Martha S., Pharoah, Paul D., Schmidt, Marjanka K., Cox, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932658/
https://ncbi.nlm.nih.gov/pubmed/21632523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2011-100018
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