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Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness

Bioengineering advances have made it possible to fundamentally alter the genetic codes of organisms. However, the evolutionary consequences of expanding an organism's genetic code with a non-canonical amino acid are poorly understood. Here we show that bacteriophages evolved on a host that inco...

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Detalhes bibliográficos
Main Authors: Hammerling, Michael J., Ellefson, Jared W., Boutz, Daniel R., Marcotte, Edward M., Ellington, Andrew D., Barrick, Jeffrey E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932624/
https://ncbi.nlm.nih.gov/pubmed/24487692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1450
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