Loading...

Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness

Bioengineering advances have made it possible to fundamentally alter the genetic codes of organisms. However, the evolutionary consequences of expanding an organism's genetic code with a non-canonical amino acid are poorly understood. Here we show that bacteriophages evolved on a host that inco...

Full description

Saved in:
Bibliographic Details
Main Authors: Hammerling, Michael J., Ellefson, Jared W., Boutz, Daniel R., Marcotte, Edward M., Ellington, Andrew D., Barrick, Jeffrey E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932624/
https://ncbi.nlm.nih.gov/pubmed/24487692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1450
Tags: Add Tag
No Tags, Be the first to tag this record!