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Immunological defect and its correction in the osteopetrotic mutant rat.

Congenital osteopetrosis in the mutant rat "op" is accompanied by early atrophy of the thymus gland. The response of thymocytes to concanavalin A and phytohemagglutinin P was greatly diminished at age 28 days, even before pronounced thymic atrophy could be detected. The response of spleen cells to m...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Milhaud, G, Labat, M L, Parant, M, Damais, C, Chedid, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1977
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/319460/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.1.339
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