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A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
Blood-brain barrier (BBB) models are often used to investigate BBB function and screen brain-penetrating therapeutics, but it has been difficult to construct a human model that possesses an optimal BBB phenotype and is readily scalable. To address this challenge, we developed a human in vitro BBB mo...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932448/ https://ncbi.nlm.nih.gov/pubmed/24561821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04160 |
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