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Chondrocyte β-Catenin Signaling Regulates Postnatal Bone Remodeling Through Modulation of Osteoclast Formation in a Murine Model

OBJECTIVE: To investigate whether β-catenin signaling in chondrocytes regulates osteoclastogenesis, thereby contributing to postnatal bone growth and bone remodeling. METHODS: Mice with conditional knockout (cKO) or conditional activation (cAct) of chondrocyte-specific β-catenin were generated. Chan...

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Detalhes bibliográficos
Main Authors: Wang, Baoli, Jin, Hongting, Zhu, Mei, Li, Jia, Zhao, Lan, Zhang, Yejia, Tang, Dezhi, Xiao, Guozhi, Xing, Lianping, Boyce, Brendan F., Chen, Di
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932359/
https://ncbi.nlm.nih.gov/pubmed/24431282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38195
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