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A mechanism of duplex DNA replication revealed by enzymatic studies of phage phi X174: catalytic strand separation in advance of replication.

The enzyme system for duplicating the duplex, circular DNA of phage phi X174 (replicative form) in stage II of the replicative life cycle was shown to proceed in two steps: synthesis of the viral (+) strand ]stage II(+)], followed by synthesis of the complementary (-) strand ]stage II(-)] [Eisenberg...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Scott, J F, Eisenberg, S, Bertsch, L L, Kornberg, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1977
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393224/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/138139/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.1.193
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