Comparison of Reverse Transcription Quantitative Real-Time PCR, Flow Cytometry, and Immunohistochemistry for Detection of Monoclonality in Lymphomas

In healthy humans, 60–70% of the B lymphocytes produce kappa light chains, while the remaining cells produce lambda light chains. Malignant transformation and clonal expansion of B lymphocytes lead to an altered kappa : lambda expression ratio, which is an important diagnostic criteria of lymphomas....

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Main Authors: Ståhlberg, Anders, Åman, Pierre, Strömbom, Linda, Zoric, Neven, Diez, Alfredo, Nilsson, Olle, Kubista, Mikael, Ridell, Börje
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932212/
https://ncbi.nlm.nih.gov/pubmed/24649374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/796210
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