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Robust Structure and Reactivity of Aqueous Arsenous Acid-Platinum(II) Anticancer Complexes

The first molecular adducts of platinum and arsenic based anticancer drugs - arsenoplatins - show unanticipated structure, substitution chemistry, and cellular cytotoxicity. The Pt(II)-As(III) bonds in these complexes are stable in aqueous solution and strongly influence the lability of the trans li...

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Detalhes bibliográficos
Main Authors: Miodragović, Ðenana U., Quentzel, Jeremy A., Kurutz, Josh W., Stern, Charlotte L., Ahn, Richard W., Kandela, Irawati, Mazar, Andrew, O’Halloran, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932145/
https://ncbi.nlm.nih.gov/pubmed/24038962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201303251
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