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Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations

PURPOSE: This study computed the risk of clinically silent adnexal neoplasia in women with germ-line BRCA1 or BRCA2 mutations (BRCA(m+)) and determined recurrence risk. METHODS: We analyzed risk reduction salpingo-oophorectomies (RRSOs) from 349 BRCA(m+) women processed by the SEE-FIM protocol and a...

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Detalhes bibliográficos
Main Authors: Conner, James R., Meserve, Emily, Pizer, Ellen, Garber, Judy, Roh, Michael, Urban, Nicole, Drescher, Charles, Quade, Bradley J., Muto, Michael, Howitt, Brooke E., Pearlman, Mark D., Berkowitz, Ross S., Horowitz, Neil, Crum, Christopher P., Feltmate, Colleen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932113/
https://ncbi.nlm.nih.gov/pubmed/24333842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2013.12.009
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