Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations

PURPOSE: This study computed the risk of clinically silent adnexal neoplasia in women with germ-line BRCA1 or BRCA2 mutations (BRCA(m+)) and determined recurrence risk. METHODS: We analyzed risk reduction salpingo-oophorectomies (RRSOs) from 349 BRCA(m+) women processed by the SEE-FIM protocol and a...

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Main Authors: Conner, James R., Meserve, Emily, Pizer, Ellen, Garber, Judy, Roh, Michael, Urban, Nicole, Drescher, Charles, Quade, Bradley J., Muto, Michael, Howitt, Brooke E., Pearlman, Mark D., Berkowitz, Ross S., Horowitz, Neil, Crum, Christopher P., Feltmate, Colleen
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932113/
https://ncbi.nlm.nih.gov/pubmed/24333842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2013.12.009
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