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Rho activation is apically restricted by Arhgap1 in neural crest cells and drives epithelial-to-mesenchymal transition

Epithelial-to-mesenchymal transitions (EMTs) are crucial for morphogenesis and carcinoma metastasis, yet mechanisms controlling the underlying cell behaviors are poorly understood. RhoGTPase signaling has been implicated in EMT; however, previous studies have yielded conflicting results regarding Rh...

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Detalhes bibliográficos
Main Authors: Clay, Matthew R., Halloran, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931734/
https://ncbi.nlm.nih.gov/pubmed/23804498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.095448
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