A Core Invasiveness Gene Signature Reflects Epithelial-to-Mesenchymal Transition but Not Metastatic Potential in Breast Cancer Cell Lines and Tissue Samples

INTRODUCTION: Metastases remain the primary cause of cancer-related death. The acquisition of invasive tumour cell behaviour is thought to be a cornerstone of the metastatic cascade. Therefore, gene signatures related to invasiveness could aid in stratifying patients according to their prognostic pr...

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Autors principals: Marsan, Melike, Van den Eynden, Gert, Limame, Ridha, Neven, Patrick, Hauspy, Jan, Van Dam, Peter A., Vergote, Ignace, Dirix, Luc Y., Vermeulen, Peter B., Van Laere, Steven J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931724/
https://ncbi.nlm.nih.gov/pubmed/24586640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089262
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