Anti-Osteoclastogenic Activity of Praeruptorin A via Inhibition of p38/Akt-c-Fos-NFATc1 Signaling and PLCγ-Independent Ca(2+) Oscillation

BACKGROUND: A decrease of bone mass is a major risk factor for fracture. Several natural products have traditionally been used as herbal medicines to prevent and/or treat bone disorders including osteoporosis. Praeruptorin A is isolated from the dry root extract of Peucedanum praeruptorum Dunn and h...

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Detalhes bibliográficos
Main Authors: Yeon, Jeong-Tae, Kim, Kwang-Jin, Choi, Sik-Won, Moon, Seong-Hee, Park, Young Sik, Ryu, Byung Jun, Oh, Jaemin, Kim, Min Seuk, Erkhembaatar, Munkhsoyol, Son, Young-Jin, Kim, Seong Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931687/
https://ncbi.nlm.nih.gov/pubmed/24586466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088974
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