Anacardic acid, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549

Objective and design: The histone acetylation processes, which are believed to play a critical role in the regulation of many inflammatory genes, are reversible and regulated by histone acetyltransferases (HATs), which promote acetylation, and histone deacetylases (HDACs), which promote deacetylatio...

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Main Authors: Yasutake, Tetsuo, Wada, Hiroo, Higaki, Manabu, Nakamura, Masuo, Honda, Kojiro, Watanabe, Masato, Ishii, Haruyuki, Kamiya, Shigeru, Takizawa, Hajime, Goto, Hajime
Format: Artigo
Jezik:Inglês
Izdano: F1000Research 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931454/
https://ncbi.nlm.nih.gov/pubmed/24627774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-78.v1
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