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Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice

The hypothesis of this study was that sustained activity of the Nod-like receptor protein (NLRP)-3 inflammasome in wounds of diabetic humans and mice contributes to the persistent inflammatory response and impaired healing characteristic of these wounds. Macrophages (Mp) isolated from wounds on diab...

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Autori principali: Mirza, Rita E., Fang, Milie M., Weinheimer-Haus, Eileen M., Ennis, William J., Koh, Timothy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931398/
https://ncbi.nlm.nih.gov/pubmed/24194505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0927
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