Interactions Among Glucose Delivery, Transport, and Phosphorylation That Underlie Skeletal Muscle Insulin Resistance in Obesity and Type 2 Diabetes: Studies With Dynamic PET Imaging

Dynamic positron emission tomography (PET) imaging was performed using sequential tracer injections ([(15)O]H(2)O, [(11)C]3-O-methylglucose [3-OMG], and [(18)F]fluorodeoxyglucose [FDG]) to quantify, respectively, skeletal muscle tissue perfusion (glucose delivery), kinetics of bidirectional glucose...

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Hauptverfasser: Goodpaster, Bret H., Bertoldo, Alessandra, Ng, Jason M., Azuma, Koichiro, Pencek, R. Richard, Kelley, Carol, Price, Julie C., Cobelli, Claudio, Kelley, David E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2014
Schlagworte:
Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931396/
https://ncbi.nlm.nih.gov/pubmed/24222345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1249
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