A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma

The genetic hallmark of Burkitt lymphoma (BL) is the t(8;14)(q24;q32) and its variants leading to activation of the MYC oncogene. It is a matter of debate whether true BL without MYC translocation exists. Here, we identified 59 lymphomas concordantly called BL by 2 gene expression classifiers among...

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Autors principals: Salaverria, Itziar, Martin-Guerrero, Idoia, Wagener, Rabea, Kreuz, Markus, Kohler, Christian W., Richter, Julia, Pienkowska-Grela, Barbara, Adam, Patrick, Burkhardt, Birgit, Claviez, Alexander, Damm-Welk, Christine, Drexler, Hans G., Hummel, Michael, Jaffe, Elaine S., Küppers, Ralf, Lefebvre, Christine, Lisfeld, Jasmin, Löffler, Markus, Macleod, Roderick A. F., Nagel, Inga, Oschlies, Ilske, Rosolowski, Maciej, Russell, Robert B., Rymkiewicz, Grzegorz, Schindler, Detlev, Schlesner, Matthias, Scholtysik, René, Schwaenen, Carsten, Spang, Rainer, Szczepanowski, Monika, Trümper, Lorenz, Vater, Inga, Wessendorf, Swen, Klapper, Wolfram, Siebert, Reiner
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931189/
https://ncbi.nlm.nih.gov/pubmed/24398325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-06-507996
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