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Next Generation Sequencing-based Parallel Analysis of Melting Kinetics of 4096 Variants of a Bacterial Promoter
Promoter melting by bacterial RNA polymerase is a key step in transcription initiation. We used Next Generation Sequencing (NGS) based approach to analyze in parallel promoter melting of all 4096 sequence variants of the 6 bp -10 promoter element. We used NGS read count for each sequence of a promot...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931131/ https://ncbi.nlm.nih.gov/pubmed/24359527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401277w |
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