Inflammation Promotes Airway Epithelial ATP Release via Calcium-Dependent Vesicular Pathways

ATP in airway surface liquid (ASL) controls mucociliary clearance functions via the activation of airway epithelial purinergic receptors. However, abnormally elevated ATP levels have been reported in inflamed airways, suggesting that excessive ATP in ASL contributes to airway inflammation. Despite t...

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Hlavní autoři: Okada, Seiko F., Ribeiro, Carla M. P., Sesma, Juliana I., Seminario-Vidal, Lucia, Abdullah, Lubna H., van Heusden, Catharina, Lazarowski, Eduardo R., Boucher, Richard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2013
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931099/
https://ncbi.nlm.nih.gov/pubmed/23763446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0493OC
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