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Inflammation Promotes Airway Epithelial ATP Release via Calcium-Dependent Vesicular Pathways

ATP in airway surface liquid (ASL) controls mucociliary clearance functions via the activation of airway epithelial purinergic receptors. However, abnormally elevated ATP levels have been reported in inflamed airways, suggesting that excessive ATP in ASL contributes to airway inflammation. Despite t...

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Detalhes bibliográficos
Main Authors: Okada, Seiko F., Ribeiro, Carla M. P., Sesma, Juliana I., Seminario-Vidal, Lucia, Abdullah, Lubna H., van Heusden, Catharina, Lazarowski, Eduardo R., Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931099/
https://ncbi.nlm.nih.gov/pubmed/23763446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0493OC
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