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Mechanism of Photosignaling by Drosophila Cryptochrome: ROLE OF THE REDOX STATUS OF THE FLAVIN CHROMOPHORE

Cryptochrome (CRY) is the primary circadian photoreceptor in Drosophila. Upon light absorption, dCRY undergoes a conformational change that enables it to bind to Timeless (dTIM), as well as to two different E3 ligases that ubiquitylate dTIM and dCRY, respectively, resulting in their proteolysis and...

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Bibliografiske detaljer
Main Authors: Ozturk, Nuri, Selby, Christopher P., Zhong, Dongping, Sancar, Aziz
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931024/
https://ncbi.nlm.nih.gov/pubmed/24379403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.542498
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