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Interaction of bleomycin with DNA.

The sequence of oligonucleotides produced by the action of bleomycin and ferrous ion on double- and single-stranded DNA has been determined. In the presence of ferrous ion, bleomycin promotes cleavage at G-T and G-C sequences, while high concentrations of ferrous ion alone result in strand scission...

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Autors principals: Takeshita, M, Grollman, A P, Ohtsubo, E, Ohtsubo, H
Format: Artigo
Idioma:Inglês
Publicat: 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC393101/
https://ncbi.nlm.nih.gov/pubmed/83650
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