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Mitochondrial oxygen consumption deficits in skeletal muscle isolated from an Alzheimer’s disease-relevant murine model

BACKGROUND: Age is considered a primary risk factor for neurodegenerative diseases including Alzheimer’s disease (AD). It is also now well understood that mitochondrial function declines with age. Mitochondrial deficits have been previously assessed in brain from both human autopsy tissue and diseas...

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Detalhes bibliográficos
Main Authors: Schuh, Rosemary A, Jackson, Kathryn C, Schlappal, Anna E, Spangenburg, Espen E, Ward, Christopher W, Park, Ji H, Dugger, Natalie, Shi, Guo Li, Fishman, Paul S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930757/
https://ncbi.nlm.nih.gov/pubmed/24524276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-24
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