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Engineering a single ubiquitin ligase for the selective degradation of all activated ErbB receptor tyrosine kinases

Interrogating specific cellular activities often entails the dissection of posttranslational modifications or functional redundancy conferred by protein families, which demands more sophisticated research tools than simply eliminating a specific gene product by gene targeting or RNAi. We have develo...

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Bibliografski detalji
Glavni autori: Kong, Fanming, Zhang, Jianxuan, Li, Yuewei, Hao, Xishan, Ren, Xiubao, Li, Hui, Zhou, Pengbo
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930622/
https://ncbi.nlm.nih.gov/pubmed/23416973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.33
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