Engineering a single ubiquitin ligase for the selective degradation of all activated ErbB receptor tyrosine kinases

Interrogating specific cellular activities often entails the dissection of posttranslational modifications or functional redundancy conferred by protein families, which demands more sophisticated research tools than simply eliminating a specific gene product by gene targeting or RNAi. We have develo...

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Bibliographic Details
Main Authors: Kong, Fanming, Zhang, Jianxuan, Li, Yuewei, Hao, Xishan, Ren, Xiubao, Li, Hui, Zhou, Pengbo
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930622/
https://ncbi.nlm.nih.gov/pubmed/23416973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.33
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