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Role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice

OBJECTIVE: Allelic variation in the α5 nicotinic acetylcholine receptor (nAChR) subunit gene, CHRNA5, increases vulnerability to tobacco addiction. Here, we investigated the role of α5* nAChRs in the effects of nicotine on brain reward systems. MATERIALS AND METHODS: Effects of acute (0.03125-0.5 mg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fowler, Christie D., Tuesta, Luis, Kenny, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930613/
https://ncbi.nlm.nih.gov/pubmed/23958943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3235-1
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