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Asthma: Gln27Glu and Arg16Gly polymorphisms of the beta2-adrenergic receptor gene as risk factors

BACKGROUND: Asthma is caused by both environmental and genetic factors. The ADRB2 gene, which encodes the beta 2-adrenergic receptor, is one of the most extensively studied genes with respect to asthma prevalence and severity. The Arg16Gly (+46A > G) and Gln27Glu (+79C > G) polymorphisms in th...

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Autors principals: de Paiva, Ana Carolina Zimiani, Marson, Fernando Augusto de Lima, Ribeiro, José Dirceu, Bertuzzo, Carmen Sílvia
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930554/
https://ncbi.nlm.nih.gov/pubmed/24499171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1710-1492-10-8
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