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Low genetic diversity and functional constraint in loci encoding Plasmodium vivax P12 and P38 proteins in the Colombian population

BACKGROUND: Plasmodium vivax is one of the five species causing malaria in human beings, affecting around 391 million people annually. The development of an anti-malarial vaccine has been proposed as an alternative for controlling this disease. However, its development has been hampered by allele-sp...

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Hlavní autoři: Forero-Rodríguez, Johanna, Garzón-Ospina, Diego, Patarroyo, Manuel A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930544/
https://ncbi.nlm.nih.gov/pubmed/24533461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-58
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