Efficient Translation of Dnmt1 Requires Cytoplasmic Polyadenylation and Musashi Binding Elements

Regulation of DNMT1 is critical for epigenetic control of many genes and for genome stability. Using phylogenetic analysis we characterized a block of 27 nucleotides in the 3′UTR of Dnmt1 mRNA identical between humans and Xenopus and investigated the role of the individual elements contained within...

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Bibliografski detalji
Glavni autori: Rutledge, Charlotte E., Lau, Ho-Tak, Mangan, Hazel, Hardy, Linda L., Sunnotel, Olaf, Guo, Fan, MacNicol, Angus M., Walsh, Colum P., Lees-Murdock, Diane J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930535/
https://ncbi.nlm.nih.gov/pubmed/24586322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088385
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